Antonin Adrien Mazoyer was born on March 17, 1887 in the town of Le Creusot (Saône-et-Loire). His father bought a shop to trade in earthenware, porcelain and glass. After his schooling, the young Adrien was naturally introduced to the commercial activities of the store. He seems to have done the Beaux-Arts, or at least followed an artistic training; study drawings made in 1906 suggest this.

In Paris, he worked in the decoration workshop dependent on Louis Damon's porcelain and art crystal sales shop "Au Vase Etrusque", located at 20 boulevard Malesherbes. He made the war and was lucky, at the armistice, to be able to return to his hometown where he took over the paternal business in 1919.

He began his artistic work by cold painting lacquer decorations on globes for lamps and glass lampshades. Faced with commercial success, he set up a workshop equipped with an oven and began producing hot enamel decorations. Self-taught, he gropes, carries out research, experiments with techniques and ends up achieving remarkable results. Its porcelain and glassware, of reliable quality, consisting mainly of vases and cups, are decorated with stylized floral decorations or geometric patterns in the Art Deco style and painted with polychrome enamels.

Active throughout the 1920s and 1930s, he presented his creations, which were noticed at various local or national exhibitions, such as the Marsan pavilion at the International Exhibition of Decorative Arts in 1925 or the Massif-Central pavilion at the International Exhibition of Arts and Techniques in 1937 in Paris. For 10 years, he exhibited at the Lyon International Fair.

He had offices at 3, rue des Jardiniers in Paris.

Adrien Mazoyer ceased his activities at the start of the war in 1940, in poor health. He died in Moulins on November 2, 1950.